99% Prohormones Peptides Follistatin 315 stimulating hormone inhibiting
Quick Details: Product name:Follistatin 315
Other name:Follistatin
N-terminal Sequence:Gly30
Predicted Molecular Mass:34.7 kDa
Molecular Weight:390
Assay:99%
Appearance:White powder
Min order: 10 vials
Delivery ways: TNT,UPS,DHL,EMS,Fedex
Payment ways: T/T,Western Union ,Money Gram and Bitcoin
Description: Follistatin is a secreted glycoprotein that was first identified as a folliclestimulating hormone inhibiting substance in ovarian follicular fluid.Human Follistatin cDNA encodes a 344 amino acid protein with a 29 aa signal sequence, an Nterminal atypical TGF binding domain, three Follistatin domains that contain EGF like and kazallike motifs, and a highly acidic Cterminal tail. Follistatin is a secreted protein that binds to ligands of the TGF-Beta family and regulates their activity by inhibiting their access to signaling receptors.
It was originally discovered as activin antagonists whose activity suppresses expression and secretion of the pituitary hormone FSH. In addition to being a natural antagonist, follistatin can inhibit the activity of other TGF-Beta ligands including BMP-2,-4,-6,-7, Myostatin, GDF-11, and TGF-Beta1. Follistatin is expressed in the pituitary, ovaries, decidual cells of the endometrium, and in some other tissues. Recombinant human Follistatin 315 is a 34.7 kDa protein containing amino acids 30-344 of the FST-344 protein.
Applications: Follistatin 344 is a naturally occurring human peptide and a potent inhibitor of myostatin. Myostatin encourages the degradation of myotubes therefore inhibition of myostatin will ultimately result in increased muscle mass by preventing degradation.Follistatin is being studied for its role in regulation of muscle growth, as an antagonist to myostatin.
Either by genetic elimination or by increasing the amount of follistatin, resulted in greatly increased muscle mass.In 2009, research with macaque monkeys demonstrated that regulating follistatin via gene therapy also resulted in muscle growth and increases in strength.A study has also shown that increased levels of follistatin, by leading to increased muscle mass of certain core muscular groups, can increase life expectancy in cases of spinal muscular atrophy in animal models.
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Product advantages:1.Our company is a professional raw powder factory in China for over 10 years, all powders are factory directly supplying.We have exported to Germany, Norway, Poland, Finland, Spain, UK, France, Russia, USA, Australia, Japan, Korea and many other countries, over 100kgs each month.
2.We can follow your instruction to pack your goods.
3.We have logistic companies to arrange the shipping .High purity,fast delivery ,safe shipping and considerate after -service gain trust and praise from customer all over the world .
4.We have resend policy ,if seized by customer ,we will resend the goods for you freely .After all, creit is important .
Professional team special for package and shipment and staring on tracking code 24hours for customs pass guaranteed. 100% pass to UK, Norway, Poland, Spain, USA, Canada, Brazil; 98% pass to Germany, Russia, Australia, New Zealand.
Most of powders are in stock, Chargeable samples are available, Could be shipped out within 24hours.
High quality, good price, fast and safety delivery. Shipment by DHL, TNT, FedEx, HKEMS, UPS, etc.